Macrocyclic peptide construction through C–H activation strategy

Highly Regioselective Arylation of sp³ C−H Bonds Catalyzed by Palladium Acetate

V. G. Zaitsev, Dmitry Shabashov, Olafs Daugulis · Journal of the American Chemical Society · 2005 · 1.5K citations

Natural Sciences, Chemistry, Catalysis +13

New peptide architectures through C–H activation stapling between tryptophan–phenylalanine/tyrosine residues

Lorena Mendive‐Tapia, Sara Preciado, Jesús García et al. · Nature Communications · 2015 · 296 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +17

Site-Selective C(sp³)–H Functionalization of Di-, Tri-, and Tetrapeptides at the N-Terminus

Wei Gong, Guofu Zhang, Tao Liu et al. · Journal of the American Chemical Society · 2014 · 283 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +13

A general strategy for synthesis of cyclophane-braced peptide macrocycles via palladium-catalysed intramolecular sp3 C−H arylation

Xuekai Zhang, Gang Lü, Meng Sun et al. · Nature Chemistry · 2018 · 244 citations

Pharmacy, Medicinal Chemistry, Synthetic Medicinal Chemistry +12

Stapled Peptides by Late‐Stage C(sp³)−H Activation

Anaïs F. M. Noisier, Jesús García, Ioana Ionuț et al. · Angewandte Chemie International Edition · 2016 · 160 citations

Pharmacy, Biochemistry, Medicinal Chemistry +13