Concepedia

BCR-ABL tyrosine kinase inhibition induces metabolic vulnerability by preventing the integrated stress response in K562 cells

Yu Kato, Kazuhiro Kunimasa, Yoshikazu Sugimoto, Akihiro Tomida

Biochemical and Biophysical Research Communications · 2018 · 14 citations · 22 references

DOI

Concepts

References

22

An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress

Heather P. Harding, Yuhong Zhang, Huiquing Zeng et al. · Molecular Cell · 2003 · 3.3K citations · Full text

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Perk Is Essential for Translational Regulation and Cell Survival during the Unfolded Protein Response

Heather P. Harding, Yuhong Zhang, Anne Bertolotti et al. · Molecular Cell · 2000 · 2K citations · Full text

, , +15

Reinitiation involving upstream ORFs regulates <i>ATF4</i> mRNA translation in mammalian cells

Krishna M. Vattem, Ronald C. Wek · Proceedings of the National Academy of Sciences · 2004 · 1.7K citations · Full text

, , +17

Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

Phoebe D. Lu, Heather P. Harding, David Ron · The Journal of Cell Biology · 2004 · 993 citations · Full text

, , +17

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

James B. Konopka, Susan M. Watanabe, Owen N. Witte · Cell · 1984 · 904 citations

, , +10