Concepedia

Combination of metformin and phenformin synergistically inhibits proliferation and hTERT expression in human breast cancer cells.

Davoud Jafari-Gharabaghlou, Younes Pilehvar‐Soltanahmadi, Mehdi Dadashpour, Ali Mota, Soheila Vafajouy-Jamshidi, Leila Faramarzi, Sara Rasouli, Nosratollah Zarghami

PubMed · 2018 · 59 citations · 35 references

DOIFull text

Open access

Abstract

It is speculated that the combination of MET and PHE may be a promising and convenient approach to improve the efficiency of breast cancer treatment.speculated that the combination of MET and PHE may be a promising and convenient approach to improve the efficiency of breast cancer treatment.

References

35

American Cancer Society Guidelines for Breast Screening with MRI as an Adjunct to Mammography

Debbie Saslow, C. Boetes, Wylie Burke et al. · CA A Cancer Journal for Clinicians · 2007 · 2.6K citations · Full text

Metformin Is an AMP Kinase–Dependent Growth Inhibitor for Breast Cancer Cells

Mahvash Zakikhani, Ryan J.O. Dowling, I. George Fantus et al. · Cancer Research · 2006 · 1K citations · Full text

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Metformin Inhibits Mammalian Target of Rapamycin–Dependent Translation Initiation in Breast Cancer Cells

Ryan J.O. Dowling, Mahvash Zakikhani, I. George Fantus et al. · Cancer Research · 2007 · 923 citations · Full text

Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro

Irina Alimova, Bolin Liu, Zeying Fan et al. · Cell Cycle · 2009 · 518 citations · Full text

Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types

Dimitrios Iliopoulos, Heather A. Hirsch, Kevin Struhl · Cancer Research · 2011 · 444 citations · Full text

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