Clinical effects of recombinant thrombomodulin and defibrotide on sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation

Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics

Yoshinobu Kanda · Bone Marrow Transplantation · 2012 · 18.7K citations

Public Health, Biostatistics, Hematology +11

Efficacy and safety of recombinant human soluble thrombomodulin (ART‐123) in disseminated intravascular coagulation: results of a phase III, randomized, double‐blind clinical trial

Hiroaki Saito, Ikuro Maruyama, S Shimazaki et al. · Journal of Thrombosis and Haemostasis · 2006 · 600 citations

Medicine, Hematology, Pharmacology +11

Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation

Mohamad Mohty, Florent Malard, Michaël Abécassis et al. · Bone Marrow Transplantation · 2016 · 529 citations · Full text

Medicine, Hematology, Early Detection +12

Phase 3 trial of defibrotide for the treatment of severe veno-occlusive disease and multi-organ failure

Paul G. Richardson, Marcie Riches, Nancy A. Kernan et al. · Blood · 2016 · 327 citations · Full text

Medicine, Internal Medicine, Pharmacotherapy +7

A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Evaluate the Safety and Efficacy of Recombinant Human Soluble Thrombomodulin, ART-123, in Patients With Sepsis and Suspected Disseminated Intravascular Coagulation*

Jean‐Louis Vincent, M Ramesh, David Ernest et al. · Critical Care Medicine · 2013 · 322 citations

Medicine, Pharmacology, Pharmacotherapy +15