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The ileum-liver Farnesoid X Receptor signaling axis mediates the compensatory mechanism of 17α-ethynylestradiol-induced cholestasis via increasing hepatic biosynthesis of chenodeoxycholic acids in rats

Chenodeoxycholic AcidsGastrointestinal PharmacologyGastroenterology17α-Ethynylestradiol-induced CholestasisCholangiopathiesCholangiocyte BiologyHepatotoxicityMetabolic SignalingHealth SciencesCompensatory MechanismOxysterolBiochemistryLiver PhysiologyPharmacologyDigestive System DiseasesBiliary TractPhysiologyMetabolismMedicine