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Adipocyte-Derived Exosomes Carrying Sonic Hedgehog Mediate M1 Macrophage Polarization-Induced Insulin Resistance via Ptch and PI3K Pathways

DOIFull Paper Access

121

Citations

27

References

2018

Year

Ming Song, Lu Han, Fangfang Chen, Di Wang, Feng Wang, Lei Zhang, Zhihao Wang, Ming Zhong, Mengxiong Tang, Wei Zhang
Cellular Physiology and Biochemistry

Abstract

Together, these data indicate that ADEs carrying Shh induce the M1 polarization of macrophages, which contributes to insulin resistance in adipocytes through the Ptch/PI3K pathway.

References

YearCitations

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