Concepedia

Publication | Open Access

Adipose Tissue Exosome-Like Vesicles Mediate Activation of Macrophage-Induced Insulin Resistance

DOIFull Paper Access

572

Citations

44

References

2009

Year

Zhongbin Deng, Anton Poliakov, Robert W. Hardy, Ronald H. Clements, Cunren Liu, Yuelong Liu, Jianhua Wang, Xiaoyu Xiang, Shuangqin Zhang, Xiaoying Zhuang,
Diabetes

Abstract

ELVs released by adipose tissue can act as a mode of communication between adipose tissues and macrophages. The obELV-mediated induction of TNF-alpha and IL-6 in macrophages and insulin resistance requires the TLR4/TRIF pathway.

References

YearCitations

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