Metabolic Shift Induced by ω -3 PUFAs and Rapamycin Lead to Cancer Cell Death

Abstract

Our study revealed that ω-3 PUFA enhanced the anti-tumor activity of Rp while minimizing its side effects in vitro and in vivo. These results provide novel insights into the mechanisms underlying the potential beneficial effects of Rp combined with ω-3 PUFAs on the prevention of breast cancer.