Concepedia

53BP1–RIF1–shieldin counteracts DSB resection through CST- and Polα-dependent fill-in

Zachary Mirman, Francisca Lottersberger, Hiroyuki Takai, Tatsuya Kibe, Yi Gong, Kaori Takai, Alessandro Bianchi, Michal Zimmermann, Daniel Durocher, Titia de Lange

Nature · 2018 · 446 citations · 30 references

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30

Mammalian Telomeres End in a Large Duplex Loop

Jack D. Griffith, Laurey Comeau, Soraya I. Rosenfield et al. · Cell · 1999 · 2.4K citations · Full text

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TRF2 Protects Human Telomeres from End-to-End Fusions

Bas van Steensel, Agata Smogorzewska, Titia de Lange · Cell · 1998 · 1.7K citations · Full text

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p53- and ATM-Dependent Apoptosis Induced by Telomeres Lacking TRF2

Jan Karlseder, Dominique Broccoli, Yumin Dai et al. · Science · 1999 · 1.1K citations

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Centrosome Amplification and a Defective G2–M Cell Cycle Checkpoint Induce Genetic Instability in BRCA1 Exon 11 Isoform–Deficient Cells

Xiaoling Xu, Steven P. Linke, Cuiling Li et al. · Molecular Cell · 1999 · 817 citations · Full text

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The shieldin complex mediates 53BP1-dependent DNA repair

Sylvie M. Noordermeer, Salomé Adam, Dheva Setiaputra et al. · Nature · 2018 · 660 citations · Full text

, , +11