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PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model

Ching‐Chi Chiu, Chin-Song Lu, Yi‐Hsin Weng, Ying‐Ling Chen, Ying‐Zu Huang, Rou-Shayn Chen, Yi‐Chuan Cheng, Yin-Cheng Huang, Yu-Chuan Liu, Szu‐Chia Lai,

Molecular Neurobiology · 2018 · 53 citations · 43 references

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References

43

α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies

Maria Grazia Spillantini, R. Anthony Crowther, Ross Jakes et al. · Proceedings of the National Academy of Sciences · 1998 · 3.2K citations

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Mitochondrial Complex I Deficiency in Parkinson's Disease

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Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

Valerian E. Kagan, Vladimir A. Tyurin, Jianfei Jiang et al. · Nature Chemical Biology · 2005 · 1.2K citations

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Prion-like spreading of pathological α-synuclein in brain

Masami Masuda‐Suzukake, Takashi Nonaka, Masato Hosokawa et al. · Brain · 2013 · 888 citations · Full text

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Characterization of PLA2G6 as a locus for dystonia‐parkinsonism

Coro Paisán-Ruı́z, Kailash P. Bhatia, Abi Li et al. · Annals of Neurology · 2008 · 482 citations

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