Agricultural and Biological Chemistry · 1984 · 19 citations · 1 references
Life SciencesBiochemistryMicrobiologyEnzymologyMetabolismMicrobial MetabolismAmino Acid FermentationAmino Acid MetabolismBacterial FermentationBacterial MetabolismMetabolic Pathways In FermentationProtein MetabolismAmino Acid Metabolism In MicrobesEssential Amino Acid MetabolismGlutamic Acid FermentationL-lysine FermentationLysine BiosynthesisLysine MetabolismMicrobial Amino Acid BiosynthesisMicrobial Amino Acid Metabolism
L-Lysine, an essential amino acid, has been obtained mainly by microbial production since Kinoshita et al.l) discovered in 1958 that a homoserine-requiring mutant of Corynebacterium glutamicum could accumulate a large amount of lysine in the medium. We have applied 13C NMR spectroscopy to studies of in vivo metabolism of the lysine producing mutant and its derivatives, as has been reported for the analysis of glutamic acid fermentation by Microbacterium ammoniaphilum.2)
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