Concepedia

Gene promoter and exon DNA methylation changes in colon cancer development – mRNA expression and tumor mutation alterations

Béla Molnár, Orsolya Galamb, Bálint Péterfia, Barnabás Wichmann, István Csabai, András Bodor, Alexandra Kalmár, Krisztina Andrea Szigeti, Barbara Kinga Barták, Zsófia Brigitta Nagy,

BMC Cancer · 2018 · 64 citations · 73 references

DOIFull text

Open access

Abstract

DNA methylation with consecutive phenotypic effect can be observed in a high number of promoter and gene body regions through CRC development.

References

73

Fast gapped-read alignment with Bowtie 2

Ben Langmead, Steven L. Salzberg · Nature Methods · 2012 · 58.3K citations · Full text

, , +7

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

Jacques Ferlay, Isabelle Soerjomataram, Rajesh Dikshit et al. · International Journal of Cancer · 2014 · 28.8K citations · Full text

, , +17

Comprehensive molecular characterization of human colon and rectal cancer

Nature · 2012 · 8.5K citations · Full text

, , +5

Genetic Alterations during Colorectal-Tumor Development

Bert Vogelstein, Eric R. Fearon, Stanley R. Hamilton et al. · New England Journal of Medicine · 1988 · 6.7K citations

, , +13

Aberrant CpG-island methylation has non-random and tumour-type–specific patterns

J Costello, Michael C. Frühwald, Dominic J. Smiraglia et al. · Nature Genetics · 2000 · 1.4K citations

, , +11