Concepedia

PINK1 protects against oxidative stress induced senescence of human nucleus pulposus cells via regulating mitophagy

Yiyang Wang, Jieliang Shen, Yanyang Chen, Huzhe Liu, Hao Zhou, Zhibiao Bai, Zhenming Hu, Xiuming Guo

Biochemical and Biophysical Research Communications · 2018 · 76 citations · 12 references

DOI

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12

Magnetic Resonance Classification of Lumbar Intervertebral Disc Degeneration

Christian W. A. Pfirrmann, Alexander Metzdorf, Marco Zanetti et al. · Spine · 2001 · 4K citations

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PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

Derek P. Narendra, Seok Min Jin, Atsushi Tanaka et al. · PLoS Biology · 2010 · 2.9K citations · Full text

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Mitochondria are required for pro‐ageing features of the senescent phenotype

Clara Correia‐Melo, Rhys Anderson, Graeme Hewitt et al. · The EMBO Journal · 2016 · 781 citations · Full text

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Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration

Christine L. Le Maitre, Anthony J. Freemont, Judith A. Hoyland · Arthritis Research & Therapy · 2007 · 453 citations · Full text

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Oxidative stress inhibits the proliferation, induces premature senescence and promotes a catabolic phenotype in human nucleus pulposus intervertebral disc cells

Anastasia Dimozi, Eleni Mavrogonatou, Aimilia D. Sklirou et al. · European Cells and Materials · 2015 · 279 citations · Full text

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