Optimized CRISPR-Cpf1 system for genome editing in zebrafish

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

Bernd Zetsche, Jonathan S. Gootenberg, Omar O. Abudayyeh et al. · Cell · 2015 · 4.7K citations · Full text

Rna Processing, Off-target Effect, Medicine +11

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

Janice S. Chen, Enbo Ma, Lucas B. Harrington et al. · Science · 2018 · 4.1K citations

Ssdna Molecules, Molecular Diagnostic Techniques, Engineering +14

CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo

Miguel A. Moreno-Mateos, Charles E. Vejnar, Jean-Denis Beaudoin et al. · Nature Methods · 2015 · 1.3K citations · Full text

Systems Biology, In Vivo Gene Therapy, Natural Sciences +8

OligoCalc: an online oligonucleotide properties calculator

Warren A. Kibbe · Nucleic Acids Research · 2007 · 1.3K citations · Full text

Distinct Hosts, Biological Database, Oligonucleotide-melting Temperatures +12

Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA

Chris D. Richardson, Graham J. Ray, Mark A. DeWitt et al. · Nature Biotechnology · 2016 · 1.2K citations

Asymmetric Donor Dna, Engineering, Medicine +9