Low back pain and disc degeneration are decreased following chronic toll-like receptor 4 inhibition in a mouse model

Quantitative assessment of tactile allodynia in the rat paw

Sandra R. Chaplan, Flemming W. Bach, J W Pogrel et al. · Journal of Neuroscience Methods · 1994 · 7.9K citations

Life Sciences, Neurobiology, Neuroscience +12

Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain

Yasuhiko Kawasaki, Zhen‐Zhong Xu, Xiaoying Wang et al. · Nature Medicine · 2008 · 748 citations · Full text

Medicine, Neurobiology, Neuroscience +17

The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy

Flobert Tanga, Nancy Nutile‐McMenemy, Joyce A. DeLeo · Proceedings of the National Academy of Sciences · 2005 · 625 citations · Full text

Life Sciences, Immunology, Neuroscience +17

Spinal Cord Toll-Like Receptor 4 Mediates Inflammatory and Neuropathic Hypersensitivity in Male But Not Female Mice

Robert E. Sorge, Michael L. LaCroix‐Fralish, Alexander H. Tuttle et al. · Journal of Neuroscience · 2011 · 468 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Localization of degradative enzymes and their inhibitors in the degenerate human intervertebral disc

Christine L. Le Maitre, Anthony J. Freemont, Judith A. Hoyland · The Journal of Pathology · 2004 · 448 citations

Medicine, Pathobiology, Pathology +17