MicroRNA-449a upregulation promotes chondrocyte extracellular matrix degradation in osteoarthritis

Radiological Assessment of Osteo-Arthrosis

Jan Kellgren, J. S. Lawrence · Annals of the Rheumatic Diseases · 1957 · 12.4K citations · Full text

Medicine, Orthopaedic Surgery, Radiology +10

Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States

Reva C. Lawrence, Charles G. Helmick, Frank C. Arnett et al. · Arthritis & Rheumatism · 1998 · 2.7K citations

Medicine, Internal Medicine, Disease Surveillance +16

Bone Morphogenetic Protein (BMP) signaling in development and human diseases

Richard N. Wang, Jordan J. Green, Zhongliang Wang et al. · Genes & Diseases · 2014 · 1K citations · Full text

Life Sciences, Developmental Biology, Genetics +17

Integrative MicroRNA and Proteomic Approaches Identify Novel Osteoarthritis Genes and Their Collaborative Metabolic and Inflammatory Networks

Dimitrios Iliopoulos, Κonstantinos Ν. Malizos, Pagona Oikonomou et al. · PLoS ONE · 2008 · 482 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

An SNP in the 5′-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage

Lorraine Southam, Julio A. Rodriguez‐Lopez, James M. Wilkins et al. · Human Molecular Genetics · 2007 · 218 citations

Life Sciences, Genetics, Molecular Genetics +13