Utility of Ruxolitinib in a Child with Chronic Mucocutaneous Candidiasis Caused by a Novel STAT1 Gain-of-Function Mutation

STAT3 Regulates Cytokine-mediated Generation of Inflammatory Helper T Cells

Xuexian O. Yang, Athanasia D. Panopoulos, Roza Nurieva et al. · Journal of Biological Chemistry · 2007 · 1.5K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Safety and Efficacy of INCB018424, a JAK1 and JAK2 Inhibitor, in Myelofibrosis

Srđan Verstovšek, Hagop M. Kantarjian, Ruben A. Mesa et al. · New England Journal of Medicine · 2010 · 1.2K citations · Full text

Medicine, Hematology, Pharmacology +13

Gain-of-function human <i>STAT1</i> mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

Luyan Liu, Satoshi Okada, Xiao‐Fei Kong et al. · The Journal of Experimental Medicine · 2011 · 798 citations · Full text

Life Sciences, Genetics, Immunology +17

Crystal Structure of a Tyrosine Phosphorylated STAT-1 Dimer Bound to DNA

Uwe Vinkemeier, Yanxiang Zhao, David Jeruzalmi et al. · Cell · 1998 · 718 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

CD49a Expression Defines Tissue-Resident CD8 + T Cells Poised for Cytotoxic Function in Human Skin

Stanley Cheuk, Heinrich Schlums, Irène Gallais Sérézal et al. · Immunity · 2017 · 652 citations · Full text

Life Sciences, Dermatology, Immunology +17