Disharmonic Inflammatory Signatures in COVID-19: Augmented Neutrophils’ but Impaired Monocytes’ and Dendritic Cells’ Responsiveness

Zuzana Paračková, Irena Zentsová, Markéta Bloomfield, +7

Cells

Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer

Michal Podrazil, Rudolf Horváth, Étienne Becht, +15

Oncotarget

Utility of Ruxolitinib in a Child with Chronic Mucocutaneous Candidiasis Caused by a Novel STAT1 Gain-of-Function Mutation

Markéta Bloomfield, Veronika Kanderová, Zuzana Paračková, +11

Journal of Clinical Immunology

Translational MedicinePathogenesisImmunologyChronic Mucocutaneous CandidiasisClinical Mycology +3

Neutrophil Extracellular Trap Induced Dendritic Cell Activation Leads to Th1 Polarization in Type 1 Diabetes

Zuzana Paračková, Irena Zentsová, Petra Vrabcová, +6

Frontiers in Immunology

Adaptive Immune SystemT-regulatory CellImmune RegulationImmunologyNet Composition +24

Highly active antimycobacterial derivatives of benzoxazine

Karel Waisser, Hana Divišová, Petra Husáková, +3

Bioorganic & Medicinal Chemistry

Medicinal ChemistryBioorganic ChemistryAntibioticsMedicineNatural Sciences +8

Enhanced STAT3 phosphorylation and PD-L1 expression in myeloid dendritic cells indicate impaired IL-27Ralpha signaling in type 1 diabetes

Zuzana Paračková, Petra Vrabcová, Irena Zentsová, +5

Scientific Reports

Novel XIAP mutation causing enhanced spontaneous apoptosis and disturbed NOD2 signalling in a patient with atypical adult-onset Crohn’s disease

Zuzana Paračková, Tomáš Milota, Petra Vrabcová, +5

Cell Death and Disease

Mutual alteration of NOD2-associated Blau syndrome and IFNγR1 deficiency

Zuzana Paračková, Markéta Bloomfield, Petra Vrabcová, +8

Journal of Clinical Immunology

Autoimmune DiseaseOphthalmologyGenetic DisorderInborn Error Of ImmunityMutual Alteration +2

Monocytes contribute to DNA sensing through the TBK1 signaling pathway in type 1 diabetes patients

Irena Zentsová, Zuzana Paračková, Jana Kayserová, +7

Journal of Autoimmunity

Type 1Human CellSignal TransductionAutoimmune DiseaseMedicine +7

Elevated Biomarkers of NETosis in the Serum of Pediatric Patients With Type 1 Diabetes and Their First-Degree Relatives

Adam Klocperk, Jana Včeláková, Petra Vrabcová, +6

Frontiers in Immunology