Concepedia

Multivalent targeting and killing of HER2 overexpressing breast carcinoma cells with methotrexate-encapsulated tetra-specific non-overlapping variable domain heavy chain anti-HER2 antibody-PEG-liposomes: In vitro proof-of-concept

Shahryar Khoshtinat Nikkhoi, Fatemeh Rahbarizadeh, Davoud Ahmadvand, S. Moein Moghimi

European Journal of Pharmaceutical Sciences · 2018 · 27 citations · 35 references

DOI

Concepts

References

35

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/<i>neu</i>Oncogene

Dennis J. Slamon, Gary M. Clark, Steven Wong et al. · Science · 1987 · 11.6K citations

Naturally occurring antibodies devoid of light chains

C. Hamers‐Casterman, T. Atarhouch, Serge Muyldermans et al. · Nature · 1993 · 3.2K citations

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Pertuzumab, Trastuzumab, and Docetaxel in HER2-Positive Metastatic Breast Cancer

Sandra M. Swain, José Baselga, Sung‐Bae Kim et al. · New England Journal of Medicine · 2015 · 2.1K citations · Full text

HER2 (neu) Signaling Increases the Rate of Hypoxia-Inducible Factor 1α (HIF-1α) Synthesis: Novel Mechanism for HIF-1-Mediated Vascular Endothelial Growth Factor Expression

Erik Laughner, Panthea Taghavi, Kelly A. Chiles et al. · Molecular and Cellular Biology · 2001 · 1.2K citations · Full text

The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

Alan L. Schechter, David F. Stern, Lalitha Vaidyanathan et al. · Nature · 1984 · 1.2K citations

, , +9