Concepedia

Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts

Timothy Nacarelli, Ashley Azar, Oya Altinok, Zulfiya Orynbayeva, Christian Sell

GeroScience · 2018 · 56 citations · 52 references

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52

The serial cultivation of human diploid cell strains

Leonard Hayflick, Paul S. Moorhead · Experimental Cell Research · 1961 · 8.4K citations

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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

Darren J. Baker, Tobias Wijshake, Tamar Tchkonia et al. · Nature · 2011 · 3.6K citations · Full text

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Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

Darren J. Baker, Bennett G. Childs, Matej Durik et al. · Nature · 2016 · 2.8K citations · Full text

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Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype

Christopher D. Wiley, Michael C. Velarde, Pacôme Lecot et al. · Cell Metabolism · 2015 · 1.2K citations · Full text

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Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson–Gilford progeria syndrome

Robert D. Goldman, Dale K. Shumaker, Michael R. Erdos et al. · Proceedings of the National Academy of Sciences · 2004 · 1.1K citations · Full text

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