Concepedia

Short-Chain Fatty Acids Alter Metabolic and Virulence Attributes of Borrelia burgdorferi

Ying-Han Lin, Yue Chen, Trever C. Smith, S. L. Rajasekhar Karna, J. Seshu

Infection and Immunity · 2018 · 25 citations · 47 references

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Concepts

Abstract

Borrelia burgdorferi responds to a variety of host-derived factors and appropriately alters its gene expression for adaptation under different host-specific conditions. We previously showed that various levels of acetate, a short-chain fatty acid (SCFA), altered the protein profile of B. burgdorferi .

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