Reno-protective effects of TAK-242 on acute kidney injury in a rat model

RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis

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Medicine, Clinical Sciences, Acute Care Medicine +12

An assessment of the RIFLE criteria for acute renal failure in hospitalized patients*

Shigehiko Uchino, Rinaldo Bellomo, Donna Goldsmith et al. · Critical Care Medicine · 2006 · 944 citations

Medicine, Internal Medicine, Nephrology +13

Acute Kidney Injury: Definition, Pathophysiology and Clinical Phenotypes.

Konstantinos Makris, Loukia Spanou · PubMed · 2016 · 694 citations

Medicine, Nephrology, Pathobiology +8

TAK-242 (Resatorvid), a Small-Molecule Inhibitor of Toll-Like Receptor (TLR) 4 Signaling, Binds Selectively to TLR4 and Interferes with Interactions between TLR4 and Its Adaptor Molecules

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Life Sciences, Immunology, Molecular Biology +17

Therapeutic effects of TAK-242, a novel selective Toll-like receptor 4 signal transduction inhibitor, in mouse endotoxin shock model

Takukyu Sha, Mie Sunamoto, Tomoyuki Kitazaki et al. · European Journal of Pharmacology · 2007 · 176 citations

Life Sciences, Immunology, Pharmacology +17