A novel method to prepare tussah/<i>Bombyx mori</i> silk fibroin-based films

Richeng Yang, Peng Wu, Xinhong Wang, Zekun Liu, Cong Zhang, Yinglu Shi, Feng Zhang, Baoqi Zuo

RSC Advances · 2018 · 23 citations · 42 references

DOIFull text

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Concepts

Abstract

/formic acid as a co-solvent and water as a rinse solvent. The morphology, crystallinity, thermal resistance, mechanical properties and water contact angle of the blend films as well as the biocompatibility were investigated. The BSF/TSF blend films displayed a smooth surface and specific nanostructure in their cross-section, originating from the nanofibril-preservation during fibroin dissolution. The water rinse process induced the formation of a stable β-sheet structure. The BSF film showed superior mechanical properties to the TSF film, and the blending with TSF led to a significant reduction in the strength and elasticity of blend films. However, adding the TSF component could regulate the hydrophilic properties and enhance cell growth on the blend films. The BSF/TSF blend films with specific nanostructure, stable secondary structure, appropriate mechanical properties, and good biocompatibility, are promising candidates for application in regenerative medicine.

References

42