Proteins Potentially Involved in Immune Evasion Strategies in <i>Sporothrix brasiliensis</i> Elucidated by Ultra-High-Resolution Mass Spectrometry

Abstract

Sporotrichosis is an important disease in Brazil that is caused by fungi of the genus Sporothrix and affects cats and humans. Our work investigated the proteins differentially expressed by S. brasiliensis in order to find out why this species is more virulent and pathogenic than S. schenckii . We verified a set of proteins that may be related to immune escape and that can explain the high virulence.