Concepedia

Knockdown of LncRNA-XIST Suppresses Proliferation and TGF-β1-Induced EMT in NSCLC Through the Notch-1 Pathway by Regulation of miR-137

Xi Wang, Guojun Zhang, Zhe Cheng, Lingling Dai, Liuqun Jia, Xiaogang Jing, Huan Wang, Rui Zhang, Meng Liu, Tianci Jiang,

Genetic Testing and Molecular Biomarkers · 2018 · 82 citations · 26 references

DOI

Abstract

We identified a branch of the XIST/miR-137/Notch-1 pathway that regulates proliferation and TGF-β1-induced EMT in NSCLC, which could be involved in NSCLC progression.

References

26

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

Jacques Ferlay, Isabelle Soerjomataram, Rajesh Dikshit et al. · International Journal of Cancer · 2014 · 28.8K citations · Full text

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Plasma long noncoding RNA protected by exosomes as a potential stable biomarker for gastric cancer

Qier Li, Yongfu Shao, Xinjun Zhang et al. · Tumor Biology · 2014 · 387 citations

Knockdown of long non-coding RNA XIST exerts tumor-suppressive functions in human glioblastoma stem cells by up-regulating miR-152

Yilong Yao, Jun Ma, Yixue Xue et al. · Cancer Letters · 2015 · 341 citations

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Long non-coding RNA NEAT1 promotes non-small cell lung cancer progression through regulation of miR-377-3p-E2F3 pathway

Cheng‐Cao Sun, Shujun Li, Feng Zhang et al. · Oncotarget · 2016 · 320 citations · Full text

JAK/STAT3 signaling is required for TGF-β-induced epithelial-mesenchymal transition in lung cancer cells

Rengyun Liu, Yuanyuan Zeng, Zhe Lei et al. · International Journal of Oncology · 2014 · 299 citations · Full text

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