Concepedia

Xist Rna

Xist RNA is a long non-coding RNA molecule that functions as a key regulatory transcript in X-chromosome inactivation by coating the inactive X chromosome and recruiting chromatin-modifying complexes to initiate transcriptional silencing.

590

Publications

58.9K

Citations

3K

Authors

826

Institutions

Publications per year

2017–2026

343

Variants

X-inactive Specific Transcript

Parents

Publications

590

Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

Jing Zhao, Bryan K. Sun, Jennifer A. Erwin et al. · Science · 2008 · 1.6K citations · Full text

, , +17

The human XIST gene: Analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus

Carolyn J. Brown, Brian Hendrich, Jim L. Rupert et al. · Cell · 1992 · 1.3K citations

, , +10

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3

Colleen A. McHugh, Chun‐Kan Chen, Amy Chow et al. · Nature · 2015 · 1.2K citations · Full text

, , +12

Requirement for Xist in X chromosome inactivation

Graeme D. Penny, Graham F. Kay, Steven A. Sheardown et al. · Nature · 1996 · 1.2K citations

, , +6

Role of Histone H3 Lysine 27 Methylation in X Inactivation

Kathrin Plath, Jia Fang, Susanna Mlynarczyk‐Evans et al. · Science · 2003 · 1.2K citations

, , +17

1–5 of 590

Authors

3K

  1. JT
    Jeannie T. Lee

    Massachusetts General Hospital, United States

    36 publications · 6.7K citations

    28

    h-index

  2. NB
    Neil Brockdorff

    University of Oxford, United Kingdom

    27 publications · 6.3K citations

    25

    h-index

  3. ÉH
    Édith Heard

    Institut Curie, France

    24 publications · 3.8K citations

    23

    h-index

  4. TB
    Tatyana B. Nesterova

    University of Oxford, United Kingdom

    18 publications · 2.2K citations

    16

    h-index

  5. AW
    Anton Wutz

    Research Institute of Molecular Pathology, Austria

    16 publications · 3K citations

    15

    h-index

1–5 of 3K

Institutions

826

  1. Harvard University

    Cambridge, United States

    38 h-index

    197 publications

    41.1K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    34 h-index

    133 publications

    36.6K citations

  3. Massachusetts General Hospital

    Boston, United States

    31 h-index

    155 publications

    33.7K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    29 h-index

    169 publications

    22.3K citations

  5. Inserm

    Paris, France

    24 h-index

    108 publications

    12.5K citations

  6. Institut Curie

    Paris, France

    17 h-index

    87 publications

    11.7K citations

  7. University of Massachusetts Chan Medical School

    Worcester, United States

    17 h-index

    76 publications

    13.2K citations

  8. University of Oxford

    Oxford, United Kingdom

    16 h-index

    122 publications

    17.2K citations

1–8 of 826

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 30 publications · 3.1K citations

    26

    h-index

  2. PubMed

    Repository · 28 publications · 971 citations

    18

    h-index

  3. Cell

    18 publications · 8.2K citations

    17

    h-index

  4. Nature Communications

    13 publications · 835 citations

    13

    h-index

  5. Cell Reports

    12 publications · 1.1K citations

    12

    h-index

1–5