Concepedia

Chemical synthesis and biological evaluation of penta- to octa- saccharide fragments of Vi polysaccharide from<i>Salmonella typhi</i>

Gao‐Lan Zhang, Meng‐Man Wei, Chengcheng Song, Yufeng Ma, Xiu‐Jing Zheng, De‐Cai Xiong, Xin‐Shan Ye

Organic Chemistry Frontiers · 2018 · 15 citations · 36 references

DOI

Concepts

Abstract

The penta- to octa-saccharide fragments of Vi polysaccharide were synthesized efficiently, and the hexasaccharide might be the minimum epitope of Vi antigen based on ELISA analysis.

References

36

A Synthetic Conjugate Polysaccharide Vaccine Against <i>Haemophilus influenzae</i> Type b

Vicente Vérez-Bencomo, Violeta Fernández-Santana, Eugenio Hardy et al. · Science · 2004 · 487 citations

, , +17

Prevention of Typhoid Fever in Nepal with the VI Capsular Polysaccharide of<i>Salmonella Typhi</i>

I L Acharya, C. U. Lowe, Rita Thapa et al. · New England Journal of Medicine · 1987 · 391 citations

, , +17

PROTECTIVE ACTIVITY OF VI CAPSULAR POLYSACCHARIDE VACCINE AGAINST TYPHOID FEVER

K P Klugman, H. J. Koornhof, Rachel Schneerson et al. · The Lancet · 1987 · 311 citations

, , +10

Immunogenicity, efficacy and serological correlate of protection of Salmonella typhi Vi capsular polysaccharide vaccine three years after immunization

Keith P. Klugman, H. J. Koornhof, John B. Robbins et al. · Vaccine · 1996 · 222 citations

, , +12

The design of semi-synthetic and synthetic glycoconjugate vaccines

Paolo Costantino, Rino Rappuoli, Francesco Berti · Expert Opinion on Drug Discovery · 2011 · 205 citations

, , +16