Concepedia

Expression analysis of the MCPH1/BRIT1 and BRCA1 tumor suppressor genes and telomerase splice variants in epithelial ovarian cancer

Rawiah Alsiary, Samantha Brownhill, Anke Brüning‐Richardson, Richard Hutson, Nicholas R. Griffin, Ewan E. Morrison, Jacquelyn Bond, Susan A. Burchill, Sandra Bell

Gene · 2018 · 18 citations · 35 references

DOI

Concepts

References

35

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

Christopher M. Counter, Ariel A. Avilion, Catherine LeFeuvre et al. · The EMBO Journal · 1992 · 2.1K citations · Full text

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The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

Michael T. Hemann, Margaret A. Strong, Ling-Yang Hao et al. · Cell · 2001 · 1.2K citations · Full text

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Isolation of a Candidate Human Telomerase Catalytic Subunit Gene, Which Reveals Complex Splicing Patterns in Different Cell Types

Andrzej Kilian, David D.L. Bowtell, Helen E. Abud et al. · Human Molecular Genetics · 1997 · 587 citations · Full text

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Akt Protein Kinase Enhances Human Telomerase Activity through Phosphorylation of Telomerase Reverse Transcriptase Subunit

Sang Sun Kang, Taegun Kwon, Do Yoon Kwon et al. · Journal of Biological Chemistry · 1999 · 475 citations · Full text

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Multiple Tumor Suppressor Pathways Negatively Regulate Telomerase

Shiaw‐Yih Lin, Stephen J. Elledge · Cell · 2003 · 428 citations · Full text

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