Expression analysis of beta-secretase 1 (BACE1) and its naturally occurring antisense (BACE1-AS) in blood of epileptic patients

Amyloid β-peptide is produced by cultured cells during normal metabolism

Christian Haass, Michael G. Schlossmacher, Albert Y. Hung et al. · Nature · 1992 · 1.9K citations

Life Sciences, Biochemistry, Cell Biology +15

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase

Mohammad Ali Faghihi, Farzaneh Modarresi, Ahmad M. Khalil et al. · Nature Medicine · 2008 · 1.4K citations · Full text

Life Sciences, Molecular Biology, Neuroscience +14

Amyloid β-Induced Neuronal Hyperexcitability Triggers Progressive Epilepsy

Rimante Minkeviciene, Sylvain Rheims, Márton B. Dobszay et al. · Journal of Neuroscience · 2009 · 675 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Bace1 modulates myelination in the central and peripheral nervous system

Xiangyou Hu, Caitlin W. Hicks, Wanxia He et al. · Nature Neuroscience · 2006 · 606 citations

Medicine, Neurobiology, Neuroscience +12

Secretion of β-amyloid precursor protein cleaved at the amino terminus of the β-amyloid peptide

Peter Seubert, Tilman Oltersdorf, M. Lee et al. · Nature · 1993 · 547 citations

Life Sciences, Biochemistry, Molecular Biology +14