HDAC1-induced epigenetic silencing of ASPP2 promotes cell motility, tumour growth and drug resistance in renal cell carcinoma

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Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis

Eri Oda, Rieko Ohki, Hideki Murasawa et al. · Science · 2000 · 2.1K citations

Life Sciences, Cell Biology, Molecular Biology +16

FDA Approval Summary: Vorinostat for Treatment of Advanced Primary Cutaneous T-Cell Lymphoma

Bhupinder Mann, John R. Johnson, Martin H. Cohen et al. · The Oncologist · 2007 · 1.4K citations · Full text

Medicine, Oncology, Pharmacotherapy +14

ASPP Proteins Specifically Stimulate the Apoptotic Function of p53

Yardena Samuels-Lev, Daniel O’Connor, Daniele Bergamaschi et al. · Molecular Cell · 2001 · 664 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas.

Taro Shuin, Keiichi Kondo, Soichiro Torigoe et al. · PubMed · 1994 · 473 citations

Medicine, Genetics, Molecular Genetics +16