Concepedia

DNase II activated by the mitochondrial apoptotic pathway regulates RIP1-dependent non-apoptotic hepatocyte death via the TLR9/IFN-β signaling pathway

Yoshinobu Saito, Hayato Hikita, Yasutoshi Nozaki, Yugo Kai, Yuki Makino, Tasuku Nakabori, Satoshi Tanaka, Ryoko Yamada, Minoru Shigekawa, Takahiro Kodama,

Cell Death and Differentiation · 2018 · 68 citations · 30 references

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30

The Danger Model: A Renewed Sense of Self

Polly Matzinger · Science · 2002 · 4.2K citations

, , +13

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

Kiichi Nakahira, Jeffrey A. Haspel, Vijay Rathinam et al. · Nature Immunology · 2010 · 3K citations · Full text

, , +15

Nonalcoholic Fatty Liver Disease: Predictors of Nonalcoholic Steatohepatitis and Liver Fibrosis in the Severely Obese

John B. Dixon, Prithi S. Bhathal, Paul E. O’Brien · Gastroenterology · 2001 · 1.4K citations

, , +13

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

Takafumi Oka, Shungo Hikoso, Osamu Yamaguchi et al. · Nature · 2012 · 1.2K citations

, , +16

Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis

Ariel E. Feldstein, Ali Canbay, Paul Angulo et al. · Gastroenterology · 2003 · 1.1K citations

, , +16