Hepatic Stellate Cells in Hepatocellular Carcinoma Promote Tumor Growth Via Growth Differentiation Factor 15 Production

Yuta Myojin, Hayato Hikita, Masaya Sugiyama, +16

Gastroenterology

Transcriptomics Identify Thrombospondin‐2 as a Biomarker for NASH and Advanced Liver Fibrosis

Kazuhiro Kozumi, Takahiro Kodama, Hiroki Murai, +17

Hepatology

CTGF Mediates Tumor–Stroma Interactions between Hepatoma Cells and Hepatic Stellate Cells to Accelerate HCC Progression

Yuki Makino, Hayato Hikita, Takahiro Kodama, +10

Cancer Research

Interleukin-6 Is a Circulating Prognostic Biomarker for Hepatocellular Carcinoma Patients Treated with Combined Immunotherapy

Yuta Myojin, Takahiro Kodama, Ryotaro Sakamori, +17

Cancers

Circulating Cell-Free DNA Profiling Predicts the Therapeutic Outcome in Advanced Hepatocellular Carcinoma Patients Treated with Combination Immunotherapy

Takayuki Matsumae, Takahiro Kodama, Yuta Myojin, +21

Cancers

ImmunologyPathologyImmunotherapyCombination ImmunotherapyPretreatment Cfdna/ctdna Profiling +15

Liver stiffness measurement by acoustic radiation force impulse is useful in predicting the presence of esophageal varices or high-risk esophageal varices among patients with HCV-related cirrhosis

Naoki Morishita, Naoki Hiramatsu, Tsugiko Oze, +9

Journal of Gastroenterology

Medical UltrasoundHepatologyLiver Stiffness MeasurementAbdominal ImagingHepatitis +7

DNase II activated by the mitochondrial apoptotic pathway regulates RIP1-dependent non-apoptotic hepatocyte death via the TLR9/IFN-β signaling pathway

Yoshinobu Saito, Hayato Hikita, Yasutoshi Nozaki, +10

Cell Death and Differentiation

Dnase IiMitochondrial FunctionMedicineTlr9/ifn-β Signaling PathwayApoptosis +6

Comparison of atezolizumab plus bevacizumab and lenvatinib in terms of efficacy and safety as primary systemic chemotherapy for hepatocellular carcinoma

Kazuki Maesaka, Ryotaro Sakamori, Ryoko Yamada, +13

Hepatology Research

Sofosbuvir plus velpatasvir treatment for hepatitis C virus in patients with decompensated cirrhosis: a Japanese real-world multicenter study

Yuki Tahata, Hayato Hikita, Satoshi Mochida, +30

Journal of Gastroenterology

HepatologyHepatitis CHepatitis C VirusViral HepatitisLiver Physiology +9

White Adipose Tissue Autophagy and Adipose-Liver Crosstalk Exacerbate Nonalcoholic Fatty Liver Disease in Mice

Sadatsugu Sakane, Hayato Hikita, Kumiko Shirai, +12

Cellular and Molecular Gastroenterology and Hepatology