RASSF6-mediated inhibition of Mcl-1 through JNK activation improves the anti-tumor effects of sorafenib in renal cell carcinoma

Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

Xiaofang Sun, Zhanhui Ou, Ruochan Chen et al. · Hepatology · 2015 · 2K citations · Full text

Life Sciences, Cell Biology, Oncology +17

Sorafenib for Treatment of Renal Cell Carcinoma: Final Efficacy and Safety Results of the Phase III Treatment Approaches in Renal Cancer Global Evaluation Trial

Bernard Escudier, Tim Eisen, Walter M. Stadler et al. · Journal of Clinical Oncology · 2009 · 1.1K citations · Full text

Medicine, Oncology, Cancer Pharmacology +8

Metallothionein‐1G facilitates sorafenib resistance through inhibition of ferroptosis

Xiaofang Sun, Xiaohua Niu, Ruochan Chen et al. · Hepatology · 2016 · 735 citations · Full text

Medicine, Oncology, Pharmacology +15

MicroRNA-216a/217-Induced Epithelial-Mesenchymal Transition Targets Pten and SMAD7 to Promote Drug Resistance and Recurrence of Liver Cancer

Hongping Xia, London Lucien Ooi, Kam M. Hui · Hepatology · 2013 · 384 citations · Full text

Medicine, Cancer Biology, Oncology +17

The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma

Satoshi Shimizu, Tetsuo Takehara, Hayato Hikita et al. · Journal of Hepatology · 2010 · 342 citations

Life Sciences, Molecular Biology, Oncology +17