Low Levels of T Cell Exhaustion in Tuberculous Lung Granulomas

Eileen A. Wong, Louis R. Joslyn, Nicole L. Grant, Edwin Klein, Philana Ling Lin, Denise E. Kirschner, JoAnne L. Flynn

Infection and Immunity · 2018 · 50 citations · 59 references

DOIFull text

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Concepts

Abstract

The hallmarks of pulmonary Mycobacterium tuberculosis infection are lung granulomas. These organized structures are composed of host immune cells whose purpose is to contain or clear infection, creating a complex hub of immune and bacterial cell activity, as well as limiting pathology in the lungs.

References

59