Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

Manfred Gossen, Heidelberg Bujard

Proceedings of the National Academy of Sciences

Viral ReplicationMolecular RegulationImmunologyMolecular BiologyEscherichia Coli +18

Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants

Bin Zhou, Yuan Lu, Kaveh Hajifathalian, +454

The Lancet

The use of animal models in diabetes research

Aileen King

British Journal of Pharmacology

Ultrasensitivity in the mitogen-activated protein kinase cascade.

Chi‐Ying F. Huang, James E. Ferrell

Proceedings of the National Academy of Sciences

Molecular BiologyOocyte MaturationCytoskeletonCellular PhysiologySignaling Pathway +16

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

Lajos Mátés, Marinee Chuah, Eyayu Belay, +16

Nature Genetics

Natural SciencesGeneticsEvolutionary BiologySynthetic BiologyBeauty Transposase +7

Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits

Kole T. Roybal, Levi J. Rupp, Leonardo Morsut, +4

Cell

Cancer ImmunosurveillanceImmunologyTumor ImmunityImmunophenotypingAntigen Processing +8

The challenge of patient adherence.

Leslie R. Martin, Summer L. Williams, Kelly B. Haskard, +1

PubMed

NursingFamily MedicinePatient AdherencePrimary CarePatient Satisfaction +13

Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37)

George G. Holz, Willem M. Kiihtreiber, Joel F. Habener

Nature

Pancreatic Beta-cellsMetabolic SyndromeInsulin ManagementDiabetesPhysiology +6

Synthetic Biology Moving into the Clinic

Warren C. Ruder, Ting Lu, James J. Collins

Science

Definitions, variants, and causes of nonadherence with medication: a challenge for tailored interventions

Jacqueline G. Hugtenburg, Marcia Vervloet, Liset van Dijk, +2

Patient Preference and Adherence