β-cell–mimetic designer cells provide closed-loop glycemic control

Mingqi Xie, Haifeng Ye, Hui Wang, +5

Science

Synthetic CircuitBiomedical EngineeringGlucose ToleranceInsulin SignalingType 1 +14

Smartphone-controlled optogenetically engineered cells enable semiautomatic glucose homeostasis in diabetic mice

Jiawei Shao, Shuai Xue, Guiling Yu, +12

Science Translational Medicine

Electrogenetic cellular insulin release for real-time glycemic control in type 1 diabetic mice

Krzysztof Krawczyk, Shuai Xue, P. Buchmann, +7

Science

Self-adjusting synthetic gene circuit for correcting insulin resistance

Haifeng Ye, Mingqi Xie, Shuai Xue, +4

Nature Biomedical Engineering

Insulin ResistanceEngineeringInsulin ManagementDiabetesSynthetic Biology +5

Caffeine-inducible gene switches controlling experimental diabetes

Daniel Bojar, Leo Scheller, Ghislaine Charpin‐El Hamri, +2

Nature Communications

Immunomimetic Designer Cells Protect Mice from MRSA Infection

Ying Liu, Peng Bai, Anne-Kathrin Woischnig, +6

Cell

A synthetic biology-based device prevents liver injury in mice

Peng Bai, Haifeng Ye, Mingqi Xie, +5

Journal of Hepatology

A Synthetic-Biology-Inspired Therapeutic Strategy for Targeting and Treating Hepatogenous Diabetes

Shuai Xue, Jianli Yin, Jiawei Shao, +6

Molecular Therapy

A fully human transgene switch to regulate therapeutic protein production by cooling sensation

Peng Bai, Ying Liu, Shuai Xue, +5

Nature Medicine

Protein SecretionSignal TransductionProtein ExpressionNatural SciencesHuman Transgene Switch +11

Treatment of chronic pain by designer cells controlled by spearmint aromatherapy

Hui Wang, Mingqi Xie, Ghislaine Charpin‐El Hamri, +2

Nature Biomedical Engineering

Pain TherapyPain ResearchPain SyndromeInterventional Pain MedicineHealth Sciences +10