Concepedia

CD4 <sup>+</sup> T cell–mediated HLA class II cross-restriction in HIV controllers

Moran Galperin, Carine Farenc, Madhura Mukhopadhyay, Dhilshan Jayasinghe, Amandine Decroos, Daniela Benati, Li Lynn Tan, Lisa Ciacchi, Hugh H. Reid, Jamie Rossjohn,

Science Immunology · 2018 · 74 citations · 28 references

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Concepts

Abstract

T cells. The public TCRs suppressed HIV replication in multiple genetic backgrounds ex vivo, emphasizing the functional advantage conferred by broad HLA class II cross-restriction.

References

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