Concepedia

p27Kip1 Modulates Axonal Transport by Regulating α-Tubulin Acetyltransferase 1 Stability

Giovanni Morelli, Aviel Even, Ivan Gladwyn‐Ng, Romain Le Bail, Michal Shilian, Juliette D. Godin, Elise Peyre, Bassem A. Hassan, Arnaud Besson, Jean‐Michel Rigo,

Cell Reports · 2018 · 40 citations · 31 references

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Abstract

stabilizes the α-tubulin acetyltransferase 1, thereby promoting the acetylation of microtubules, a post-translational modification required for proper axonal transport.

References

31

HDAC6 is a microtubule-associated deacetylase

Charlotte Hubbert, Amaris R. Guardiola, Rong Shao et al. · Nature · 2002 · 2.4K citations

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A Syndrome of Multiorgan Hyperplasia with Features of Gigantism, Tumorigenesis, and Female Sterility in p27 -Deficient Mice

Matthew L. Fero, Michael J. Rivkin, Michael Tasch et al. · Cell · 1996 · 1.5K citations · Full text

, , +17

Huntingtin Controls Neurotrophic Support and Survival of Neurons by Enhancing BDNF Vesicular Transport along Microtubules

Laurent Gauthier, Bénédicte C. Charrin, María Borrell-Pagés et al. · Cell · 2004 · 1.1K citations · Full text

, , +14

Microtubule Acetylation Promotes Kinesin-1 Binding and Transport

Nathan Reed, Dawen Cai, T. Lynne Blasius et al. · Current Biology · 2006 · 903 citations · Full text

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Histone Deacetylase 6 Inhibition Compensates for the Transport Deficit in Huntington's Disease by Increasing Tubulin Acetylation

Jim Dompierre, Juliette D. Godin, Bénédicte C. Charrin et al. · Journal of Neuroscience · 2007 · 776 citations · Full text

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