Concepedia

The fission yeast Stn1-Ten1 complex limits telomerase activity via its SUMO-interacting motif and promotes telomeres replication

Samah Matmati, Mélina Vaurs, José Miguel Escandell, Laetitia Maestroni, Toru Nakamura, Miguel Godinho Ferreira, Vincent Géli, Stéphane Coulon

Science Advances · 2018 · 33 citations · 50 references

DOIFull text

Open access

Concepts

Abstract

mutant. Together, our results show that the Stn1-Ten1 complex has a dual function at telomeres by limiting telomerase action and promoting chromosome end replication.

References

50

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Identification of a SUMO-binding motif that recognizes SUMO-modified proteins

Jing Song, Linda K. Durrin, Thomas A. Wilkinson et al. · Proceedings of the National Academy of Sciences · 2004 · 583 citations · Full text

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Specification of SUMO1- and SUMO2-interacting Motifs

Christina-Maria Hecker, Matthias Rabiller, Kaisa Haglund et al. · Journal of Biological Chemistry · 2006 · 581 citations · Full text

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Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis

Yoshitami Hashimoto, Arnab Ray Chaudhuri, Massimo Lopes et al. · Nature Structural & Molecular Biology · 2010 · 548 citations

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Efficient targeted integration at leu1-32 and ura4-294 in Schizosaccharomyces pombe.

Jill B. Keeney, Jef D. Boeke · Genetics · 1994 · 389 citations · Full text

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