Mevalonate pathway blockage enhances the efficacy of mTOR inhibitors with the activation of retinoblastoma protein in renal cell carcinoma

Cancer Statistics, 2008

Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2008 · 10.2K citations · Full text

Cancer Statistics, Epidemiology, Cancer Epidemiology +14

Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex

Dos D. Sarbassov, David A. Guertin, Siraj M. Ali et al. · Science · 2005 · 6.1K citations

Molecular Biology, Tumor Biology, Signaling Pathway +16

The Global Burden of Cancer 2013

Christina Fitzmaurice, Daniel Dicker, Amanda Pain et al. · JAMA Oncology · 2015 · 2.7K citations · Full text

mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt

Kathryn O’Reilly, F. Rojo, Qing‐Bai She et al. · Cancer Research · 2006 · 2.5K citations · Full text

Interferon-Alfa as a Comparative Treatment for Clinical Trials of New Therapies Against Advanced Renal Cell Carcinoma

Robert J. Motzer, Jennifer Bacik, Barbara A. Murphy et al. · Journal of Clinical Oncology · 2002 · 1.5K citations