Concepedia

Mevalonate Pathway

Mevalonate Pathway is a metabolic pathway constituting the biochemical route by which acetyl-CoA is transformed into isopentenyl pyrophosphate through mevalonate as a key intermediate, distinguishing it as the foundational route for terpenoid and sterol biosynthesis in eukaryotes.

1.9K

Publications

119K

Citations

8.6K

Authors

2K

Institutions

Publications per year

2017–2026

455

Variants

Hmg-coa Reductase PathwayMevalonate-dependent Pathway

Parents

Publications

1.9K

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

Vincent J. J. Martin, Douglas J. Pitera, Sydnor T. Withers et al. · Nature Biotechnology · 2003 · 1.7K citations

, , +14

THE 1-DEOXY-D-XYLULOSE-5-PHOSPHATE PATHWAY OF ISOPRENOID BIOSYNTHESIS IN PLANTS

Hartmut K. Lichtenthaler · Annual Review of Plant Physiology and Plant Molecular Biology · 1999 · 1.4K citations

, , +17

Nitrogen-Containing Bisphosphonates Inhibit the Mevalonate Pathway and Prevent Post-Translational Prenylation of GTP-Binding Proteins, Including Ras

Steven P. Luckman, D. E. Hughes, Fraser P. Coxon et al. · Journal of Bone and Mineral Research · 1998 · 1.2K citations · Full text

, , +17

Inhibitors of the Nonmevalonate Pathway of Isoprenoid Biosynthesis as Antimalarial Drugs

Hassan Jomaa, Jochen Wiesner, Silke Sanderbrand et al. · Science · 1999 · 1.2K citations

, , +17

Isoprenoid biosynthesis: The evolution of two ancient and distinct pathways across genomes

B. Markus Lange, Tamas Rujan, William Martin et al. · Proceedings of the National Academy of Sciences · 2000 · 870 citations · Full text

, , +14

1–5 of 1.9K

Authors

8.6K

  1. MR
    Michel Rohmer

    Centre National de la Recherche Scientifique, France

    24 publications · 3.4K citations

    23

    h-index

  2. JD
    Jay D. Keasling

    University of California, Berkeley, United States

    25 publications · 5.5K citations

    23

    h-index

  3. TK
    Tomohisa Kuzuyama

    The University of Tokyo, Japan

    19 publications · 1.8K citations

    19

    h-index

  4. VW
    Victor W. Rodwell

    Purdue University West Lafayette, United States

    19 publications · 784 citations

    16

    h-index

  5. HS
    Haruo Seto

    The University of Tokyo, Japan

    18 publications · 1.7K citations

    16

    h-index

1–5 of 8.6K

Institutions

2K

  1. University of California, Berkeley

    Berkeley, United States

    30 h-index

    79 publications

    17.2K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    28 h-index

    133 publications

    12.8K citations

  3. The University of Tokyo

    Tokyo, Japan

    27 h-index

    133 publications

    10.1K citations

  4. Lawrence Berkeley National Laboratory

    Berkeley, United States

    23 h-index

    114 publications

    10.7K citations

  5. Chinese Academy of Sciences

    Beijing, China

    23 h-index

    174 publications

    24.9K citations

  6. Inserm

    Paris, France

    22 h-index

    120 publications

    7K citations

  7. The University of Texas Southwestern Medical Center

    Dallas, United States

    19 h-index

    53 publications

    5.1K citations

  8. Joint BioEnergy Institute

    Emeryville, United States

    19 h-index

    135 publications

    11.7K citations

1–8 of 2K

Venues

  1. Journal of Biological Chemistry

    JBC · 127 publications · 9.8K citations

    60

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 56 publications · 10K citations

    44

    h-index

  3. PubMed

    Repository · 53 publications · 3.1K citations

    26

    h-index

  4. Journal of Lipid Research

    JLR · 38 publications · 2.4K citations

    25

    h-index

  5. Journal of Bacteriology

    JB · 29 publications · 2K citations

    24

    h-index

1–5