High throughput scaffold-based 3D micro-tumor array for efficient drug screening and chemosensitivity testing

Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors

Lecia V. Sequist, Belinda A. Waltman, Dora Dias‐Santagata et al. · Science Translational Medicine · 2011 · 3.6K citations · Full text

Medicine, Genetics, Oncology +17

Organoid Models of Human and Mouse Ductal Pancreatic Cancer

Sylvia F. Boj, Chang‐Il Hwang, Lindsey A. Baker et al. · Cell · 2014 · 2.2K citations · Full text

Medicine, Cell Biology, Oncology +14

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

Norman Sachs, Joep de Ligt, Oded Kopper et al. · Cell · 2017 · 2K citations · Full text

Medicine, Cancer Biology, Oncology +12

Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

Laura Broutier, Gianmarco Mastrogiovanni, Monique M.A. Verstegen et al. · Nature Medicine · 2017 · 1.5K citations · Full text

Medicine, Cell Biology, Oncology +17

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell–Dependent Antitumor Immunity

Julie Vincent, Grégoire Mignot, Fanny Chalmin et al. · Cancer Research · 2010 · 1.2K citations

Medicine, Immunology, Oncology +17