Concepedia

The stimulatory G protein Gsα is required in melanocortin 4 receptor–expressing cells for normal energy balance, thermogenesis, and glucose metabolism

Brandon Podyma, Hui Sun, Eric Wilson, Bradley Carlson, Ethan Pritikin, Oksana Gavrilova, Lee S. Weinstein, Min Chen

Journal of Biological Chemistry · 2018 · 50 citations · 44 references

DOIFull text

Open access

Concepts

Abstract

α knockout mice and probably in individuals with Albright hereditary osteodystrophy as well.

References

44

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

Linda Madisen, Theresa A. Zwingman, Susan M. Sunkin et al. · Nature Neuroscience · 2009 · 7.4K citations · Full text

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Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice

Dennis Huszar, Catherine Lynch, Victoria Fairchild-Huntress et al. · Cell · 1997 · 3K citations · Full text

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Clinical Spectrum of Obesity and Mutations in the Melanocortin 4 Receptor Gene

I. Sadaf Farooqi, Julia M. Keogh, Giles S.H. Yeo et al. · New England Journal of Medicine · 2003 · 1.8K citations · Full text

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Divergence of Melanocortin Pathways in the Control of Food Intake and Energy Expenditure

Nina Balthasar, Louise T. Dalgaard, Charlotte E. Lee et al. · Cell · 2005 · 1.1K citations · Full text

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Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain.

Kathleen G. Mountjoy, Marty Mortrud, Malcolm J. Low et al. · Molecular Endocrinology · 1994 · 1.1K citations · Full text

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