Concepedia

Synthesis, cytotoxicity and structure-activity relationship of indolizinoquinolinedione derivatives as DNA topoisomerase IB catalytic inhibitors

Yu Qian, Hui Yang, Teng-Wei Zhu, Lemao Yu, Jianwen Chen, Lian‐Quan Gu, Zhi‐Shu Huang, Lin‐Kun An

European Journal of Medicinal Chemistry · 2018 · 10 citations · 26 references

DOI

Concepts

References

26

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.

James Carmichael, William DeGraff, Adi F. Gazdar et al. · PubMed · 1987 · 3.8K citations

, , +11

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

Y H Hsiang, Robert Hertzberg, Sidney M. Hecht et al. · Journal of Biological Chemistry · 1985 · 2.4K citations · Full text

, , +15

Structure and mechanism of DNA topoisomerase II

James M. Berger, S.J. Gamblin, Stephen C. Harrison et al. · Nature · 1996 · 856 citations

, , +12

The mechanism of topoisomerase I poisoning by a camptothecin analog

Bart L. Staker, Kathryn A. Hjerrild, M.D. Feese et al. · Proceedings of the National Academy of Sciences · 2002 · 802 citations · Full text

, , +14

A Model for the Mechanism of Human Topoisomerase I

Lance Stewart, Matthew R. Redinbo, Xiayang Qiu et al. · Science · 1998 · 703 citations

, , +14