Tanshinone IIA suppresses FcεRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway

Resveratrol improves health and survival of mice on a high-calorie diet

Joseph A. Baur, Kevin Pearson, Nathan L. Price et al. · Nature · 2006 · 4.2K citations · Full text

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AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

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Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation

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Sirt1 protects against high-fat diet-induced metabolic damage

Paul T. Pfluger, Daniel Herranz, Susana Velasco-Miguel et al. · Proceedings of the National Academy of Sciences · 2008 · 931 citations · Full text

Life Sciences, Biochemistry, Nutritional Sciences +16

SIRT1 Modulation of the Acetylation Status, Cytosolic Localization, and Activity of LKB1

José M. Cacicedo, Neil B. Ruderman, Yasuo Ido · Journal of Biological Chemistry · 2008 · 825 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14