Concepedia

Schisandrin B ameliorated chondrocytes inflammation and osteoarthritis via suppression of NF-κB and MAPK signal pathways

Jisheng Ran, Chiyuan Ma, Kai Xu, Langhai Xu, Yuzhe He, Safwat Adel Abdo Moqbel, Pengfei Hu, Lifeng Jiang, Weiping Chen, Jiapeng Bao,

Drug Design Development and Therapy · 2018 · 96 citations · 17 references

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Abstract

Our study demonstrated that Schisandrin B ameliorated chondrocytes inflammation and OA via suppression of nuclear factor-κB (NF-κB) and MAPK signal pathways, indicating a therapeutic potential in OA treatment.

References

17

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Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

Marie Cargnello, Philippe P. Roux · Microbiology and Molecular Biology Reviews · 2012 · 180 citations · Full text

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