Concepedia

A Hierarchical, Data-Driven Approach to Modeling Single-Cell Populations Predicts Latent Causes of Cell-To-Cell Variability

Carolin Loos, Katharina Moeller, Fabian Fröhlich, Tim Hucho, Jan Hasenauer

Cell Systems · 2018 · 58 citations · 44 references

Open access

Concepts

Life SciencesBiologyCell BiologyComputational BiologySingle-cell BioinformaticsSingle-cell Systems BiologyCell Population DynamicsCell-state HeterogeneitySingle-cell AnalysisSingle-cell ClusteringCell-to-cell HeterogeneityCell-to-cell VariabilityLatent Cell-state ModelingSingle-cell Variability

References

44

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Natural Sciences, Behavioral Sciences, Bayesian Biostatistics +11

Exact stochastic simulation of coupled chemical reactions

Daniel T. Gillespie · The Journal of Physical Chemistry · 1977 · 10.6K citations

Natural Sciences, Chemistry, Chemical Kinetics +8

Reversible jump Markov chain Monte Carlo computation and Bayesian model determination

Peter J. Green · Biometrika · 1995 · 5.9K citations

Computing, Biostatistics, Computer Science +17

Stochastic Gene Expression in a Single Cell

Michael B. Elowitz, Arnold J. Levine, Eric D. Siggia et al. · Science · 2002 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

Understanding predictive information criteria for Bayesian models

Andrew Gelman, Jessica Hwang, Aki Vehtari · Statistics and Computing · 2013 · 2.2K citations

Computing, Biostatistics, Bayesian Data Analysis +13