Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung - Concepedia

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Publication | Open Access

Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung

DOI Full Paper Access

59

Citations

52

References

2018

Year

Aristides D. Tagalakis, Mustafa M. Munye, R. N. Ivanova, Hanpeng Chen, Claire M. Smith, Ahmad M. Aldossary, Luca Rosa, Dale Moulding, Josephine L. Barnes, Konstantinos N. Kafetzis,

Abstract

Nanoparticle-mediated delivery of ENaCsiRNA to ALI cultures corrected aspects of the mucociliary defect in human CF cells and offers effective delivery and silencing in vivo.

References

	Year	Citations

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