Concepedia

Nobiletin attenuates neurotoxic mitochondrial calcium overload through K<sup>+</sup> influx and ΔΨ<sub>m</sub> across mitochondrial inner membrane

Ji Hyung Lee, Khulan Amarsanaa, Jinji Wu, Sang-Chan Jeon, Yanji Cui, Sung‐Cherl Jung, Deok-Bae Park, Se-Jae Kim, Sang-Heon Han, Hyun‐Wook Kim,

Korean Journal of Physiology and Pharmacology · 2018 · 21 citations · 18 references

DOIFull text

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Concepts

Abstract

channels. However, further detailed studies should be conducted to determine exact molecular targets of nobiletin in mitochondria.

References

18

Measurement of Mitochondrial Membrane Potential Using Fluorescent Rhodamine Derivatives

Russell C. Scaduto, Lee W. Grotyohann · Biophysical Journal · 1999 · 1.2K citations · Full text

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Nobiletin, a Citrus Flavonoid, Improves Memory Impairment and Aβ Pathology in a Transgenic Mouse Model of Alzheimer’s Disease

Hiroshi Onozuka, Akira Nakajima, Kentaro Matsuzaki et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 220 citations

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Mitochondrial Ca2+ Overload Underlies Aβ Oligomers Neurotoxicity Providing an Unexpected Mechanism of Neuroprotection by NSAIDs

Sara Sanz‐Blasco, Ruth A. Valero, Ignacio Rodríguez‐Crespo et al. · PLoS ONE · 2008 · 218 citations · Full text

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Constriction of the mitochondrial inner compartment is a priming event for mitochondrial division

Bongki Cho, Hyo Min Cho, Youhwa Jo et al. · Nature Communications · 2017 · 168 citations · Full text

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Nobiletin and its related flavonoids with CRE-dependent transcription-stimulating and neuritegenic activities

Hiroyuki Nagase, Naoki Omae, Akiko Omori et al. · Biochemical and Biophysical Research Communications · 2005 · 151 citations

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