Concepedia

Degradation product characterization of therapeutic oligonucleotides using liquid chromatography mass spectrometry

Nancy Magdy, Amira M. El-Kosasy, Michael G. Bartlett

Analytical and Bioanalytical Chemistry · 2018 · 29 citations · 22 references

DOI

Concepts

References

22

Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)

Kermit K. Murray, Robert K. Boyd, Marcos N. Eberlin et al. · Pure and Applied Chemistry · 2013 · 675 citations · Full text

, , +17

Studies on depurination of DNA by heat

Sheldon Greer, Stephen Zamenhof · Journal of Molecular Biology · 1962 · 184 citations

, , +6

Non-Enzymatic Depurination of Nucleic Acids: Factors and Mechanisms

Ran An, Yu Jia, Baihui Wan et al. · PLoS ONE · 2014 · 151 citations · Full text

, , +15

Mechanistic studies on depurination and apurinic site chain breakage in oligodeoxyribonucleotides

Toshinori Suzuki, Shinzo Ohsumi, Keisuke Makino · Nucleic Acids Research · 1994 · 130 citations · Full text

, , +17

Advances in Antisense Oligonucleotide Development for Target Identification, Validation, and as Novel Therapeutics

Moizza Mansoor, Alirio J. Melendez · Gene Regulation and Systems Biology · 2008 · 112 citations · Full text

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